GastroEsophageal Reflux Disease (GERD) is a condition in which there is backward flow of acid from the stomach. This causes heartburn and injury of the food pipe (esophagus).

Pantodac DSR – This allopathic medicine is suggested by doctors (outside USA) as a cure for Dyspesia and Gastro-oesophageal reflux disease. This is generally available in third-world countries like India and Bangladesh.


Dyspepsia is a common term used to describe sensation of pain or discomfort in the upper abdomen. The pain is often recurring. It can also be defined as a heterogeneous group of abdominal symptoms.


Gastro-oesophageal reflux disease (GORD) is a common condition where acid from the stomach leaks out of the stomach and up into the oesophagus (gullet).

Composition of PANTODAC-DSR

A tab/cap of PANTODAC-DSR contains pantoprazole 40 mg and domperidone 10 mg:

Domperidone – Belongs to the class of propulsives. It is used in the treatment of functional gastrointestinal disorders.
Pantoprazole – Belongs to the class of proton pump inhibitors. It is used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).

What is Pantoprazole? Allopathic Medicine for Acidity and Gas

Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. Proton-pump inhibitors (PPIs) are a class of drugs. Their main action is to have a significant and long-lasting effect. It reduces the gastric acid production. They are the most potent inhibitors of acid secretion available.


The clinical response to acidity treatment correlates directly with the degree of restraint of acid secretion achieved. Acid inhibition when maintained at the intragastric pH of value greater than 4 for at least 16 h/day seems to heal even the most complicated acid-related diseases.

It has also been shown that the degree of blockage of acid secretion in response to anti-secretory treatment depends on the genetic characteristics of the patient and on the presence of Helicobacter pylori infection.

A possible definition of potent (or profound) acid inhibition is, therefore, the achievement of the aforementioned level of control of acid secretion regardless of patient characteristics or of the presence of H. pylori infection.

It was first marketed under the brand name Protonix.

Pantoprazole is used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. Initial treatment is generally of eight weeks’ duration, after which another eight-week course of treatment may be considered if necessary.

It is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome. Pantoprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.

Pantoprazole is a selective “proton pump inhibitor”, a medicine which reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine.

What is the Dosage to be used?

The usual Adult Dose for Gastroesophageal Reflux Disease is –

Parenteral: 40 mg once a day for 7 to 10 days, administered via intravenous infusion over a period of 15 minutes. Intravenous therapy should be discontinued as soon as the patient is able to resume oral therapy.

Oral: 40 mg orally once a day, for short-term administration (up to 8 weeks); however an additional 8 weeks may be considered for patients who have not healed after the initial treatment. Safety and efficacy beyond 16 weeks of therapy have not been established.

What are the side-effects?

  • weight changes;
  • nausea, vomiting, mild diarrhea;
  • gas, stomach pain;
  • dizziness, drowsiness, tired feeling;
  • joint pain; or.
  • sleep problems (insomnia).

This YouTube video is a talk by John E.Pandolfino, Professor of Medicine at Northwestern University-Feinberg School of Medicine on the efficacy of antacid medications and long-term side-effects of PPIs which are used as allopathic medicine for acidity and gas.

Avoid Pantoprazole if –

  • you are allergic (hypersensitive) to pantoprazole, sorbitol or to any of the other ingredients of Pantoprazole.
  • you are allergic to medicines containing other proton pump inhibitors.

Take special care with Pantoprazole

If you have severe liver problems. Please tell your doctor if you ever had problems with your liver in the past. He will check your liver enzymes more frequently, especially when you are taking Pantoprazole as a long-term treatment. In the case of a rise of liver enzymes the treatment should be stopped.

If you have reduced body stores or risk factors for reduced vitamin B12 and receive pantoprazole long-term treatment. As with all acid reducing agents, pantoprazole may lead to a reduced absorption of vitamin B12.

If you are taking a medicine containing atazanavir (for the treatment of HIV-infection) at the same time as pantoprazole, ask your doctor for specific advice.

Tell your doctor immediately if you notice any of the following symptoms:

  • an unintentional loss of weight
  • repeated vomiting
  • difficulty in swallowing
  • vomiting blood
  • you look pale and feel weak (anaemia)
  • you notice blood in your stools
  • severe and/or persistent diarrhoea, as Pantoprazole has been associated with a small increase in infectious diarrhoea.

Doctor Suggestions

Gastroenterologist Dr Jose Filipe Alvares says the best thing to do is avoid milk, cheese, milk sweets, chappatis, and chana.

The following are the replies to some of the patients suffering from acidity and gas.

ajay1958 asked, Hi Doctor, Bitter taste in the mouth and dryness with upset stocmach. What should I do?
Dr Jose Filipe Alvares answers, Take Pantocid-DSR 1-0-0 before breakfast for a month. Use a pillow while sleeping.


vikram_kt asked, Sir i generally eat at home but still i have slight pain and gestric always and this problem is severe in summers.
Dr Jose Filipe Alvares answers, Get an ultrasound of the abdomen done. Start on Pantodac (40 mg) 1-0-0 before breakfast for a month.

vinay asked, hello sir i am suffering from acidity from past couple of years,always i feel bitter taste in tongue..when it is peak i wil get headache and it wont go for two days..i shown it to homepathi doctor but he told it wil take 1 month ther any permanet remeady in alopathy?
Dr Jose Filipe Alvares answers, Unfortunately, there is no permanent medication. You could try taking Pantocid-DSR 1-0-0 before breakfast for two to three weeks. Kindly note that this will not take care of the headaches.

What are the Reviews for Pantoprazole from Patients on

This allopathic medicine has a rating of 8.4 out of 10 on There are about 64 user ratings with 42 user reviews. Around 75% of the people have given a rating above 9.

A few of the comments published on this site for Pantoprazole are like this –

This is a wonderful medication. I used to have GERD, and now I can eat anything, Mexican food, spicy food, sweets, anything and it does not bother me.

Pantoprazole helped with the acid reflux. My problem started four years into taking it. For months I experienced flu like symptoms, such as muscle and joint aches, diarrhea, weakness and extreme fatigue. After MANY tests were done, I was told that I was vitamin D deficient. I know that any meds that control stomach acid also block the absorption of vitamins and things your body needs. I stopped taking Pantoprazole and was put on prescription vitamin D. After just one week, I felt like a new person. I cut out foods that bother my stomach and cut my portions in half. I may have to chew a Tums once in a while, but I feel great. So watch how long your doctor has you on this drug. It took four years to have the side effects that I had.

Protonix (pantoprazole): Worked at first to bring heartburn/acid re-flux under control, however I had to stop taking it because it started causing severe stomach & abdominal pain. Now control through diet & Tums EX. The pain from the Protonix side effect was terrible when it started happening.


“Domperidone is not permitted to be used in the United States due to its inherent risks to heart. Its import from other countries is banned by custom regulations. The Fixed-Dose Combination of pantoprazole with domperidone is medically irrational.”